Raynaud, Christophe MichelAhmad, Faizzan SyedAllouba, MonaAbou-Saleh, HaissamLui, Kathy O.Yacoub, Magdi2015-04-012014Raynaud, Christophe Michel, Faizzan Syed Ahmad, Mona Allouba, Haissam Abou-Saleh, Kathy O. Lui, and Magdi Yacoub. 2014. “Reprogramming for cardiac regeneration.” Global Cardiology Science & Practice 2014 (3): 309-329. doi:10.5339/gcsp.2014.44. http://dx.doi.org/10.5339/gcsp.2014.44.2305-7823http://nrs.harvard.edu/urn-3:HUL.InstRepos:14351139Treatment of cardiovascular diseases remains challenging considering the limited regeneration capacity of the heart muscle. Developments of reprogramming strategies to create in vitro and in vivo cardiomyocytes have been the focus point of a considerable amount of research in the past decades. The choice of cells to employ, the state-of-the-art methods for different reprogramming strategies, and their promises and future challenges before clinical entry, are all discussed here.en-USJournal Article2015-04-0110.5339/gcsp.2014.44